Alzheimer’s disease and Cannabis’s positive effects and Scientific Journal Supporting Info

Alzheimer’s disease and Cannabis’s positive effects and Scientific Journal Supporting Info
Lisa M. Eubanks, PhD, Staff Scientist at the Skaggs Institute for Chemical Biology, et al and the Scripps Research Institute stated in an Aug 2006 article titled “A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Pathology,” published in Molecular Pharmaceutics:

“In contrast to previous studies aimed at utilizing cannabinoids in Alzheimer’s disease therapy, our results provide a mechanism whereby the THC molecule can directly impact Alzheimer’s disease pathology…

It is noteworthy that THC is a considerably more effective inhibitor… than the approved drugs for Alzheimer’s disease treatment, donepezil and tacrine, which reduced [protein deposits in the brain] by only 22% and 7%, respectively, at twice the concentration used in our studies…

THC and its analogues may provide an improved therapeutic for Alzheimer’s disease [by] simultaneously treating both the symptoms and progression of Alzheimer’s disease.”

Aug. 9, 2006 – Source Info Click Here

 

Maria L. de Ceballos, PhD, Group Leader in the Department of Neural Plasticity at the Cajal Institute in Spain, et al., wrote in their Feb. 23, 2005 Journal of Neuroscience article titled “Prevention of Alzheimer’s disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockage of Microglial Activation”:
“Our results indicate that cannabinoid receptors are important in the pathology of AD [Alzheimer’s disease] and that cannabinoids succeed in preventing the neurodegenerative process occurring in the disease.
Feb. 23, 2005 – Source Info Click Here

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